25 thg 12, 2014

USE OF DRUG TREATMENT allergic rhinitis sensibly

What medications are indicated for the treatment of allergic rhinitis? Using drugs how to effectively without harmful?
 
Patients with allergic rhinitis but no cure, but if we know how to use medications correctly and the correct technique will significantly curb the symptoms of the disease. The drug is often used in sour allergic rhinitis include antihistamines group against itchy nose, runny nose; Anti-smoking groups

vasoconstrictive nasal congestion; inhaled corticosteroids are used to group. Besides the effects of medication that it also some disadvantages that if we use improper very harmful for health. So you need to master the technique, as well as taking the right medication dosage.

Group antihistamines

Anti itchy nose, runny nose, watery eyes, but not as a vasoconstrictor should not be stuffy fight. Using the older generation (chlopheniramin) cause drowsiness, can not be used for driving, operating machinery, should focus. Using a new generation (Claritin, acrivastin) does not cause drowsiness, more convenient.

Group against congestion

Natrichlorid: natriclorid isotonic solution (0.9%) as against vasoconstrictor should be stuffy. No toxic. For adults and children, including the newborn.

Naphazoline: do sympathomimetic vasoconstrictor spot up against stuffy nose. Use the form of nose drops from 0.05 to 0.1% for adults. For children: sympathomimetic but also cause stronger, primarily local effects vasoconstriction strong, do not give blood to the nasal mucosa, causing necrosis; then absorbed into the inside, causing headaches, dizziness, hypertension, tachycardia, agitation, anxiety; especially vasoconstriction in the brain, heart, scalp can lead to death.

Not suitable for children under 15 years of age.

Xyclomethazolin: due to vasoconstriction should fight congestion. For adults or children, but no more than 3 days. Not recommended for children under 2 years of age.

Phenylephrine: increased secretion of adrenaline causes vasoconstriction phenomenon adrenegic do, reduce congestion, nasal congestion control. However, this phenomenon is due to the increase in blood pressure, glaucoma, can not be used for people with hypertension who are taking MAO depression. Children are very sensitive to phenylephrine, especially when young, without self-control risk, will be toxic in place as well as the whole body. Although many documents only prohibited for children under 3 years of age, allowing for older children with lower levels, but most clinicians are not recommended for children. Adult each time only one nostril, daily dose should not exceed 5 times.

General characteristics of the old class of drugs can reduce some symptoms, causes "used" drugs, even reactive "bounced" medicine, make worse. However, due to cheap drug found effective even though temporary, it is still commonly used.

Group inhaled corticosteroids

Prolonged oral corticosteroids, continuity can help patients, but this exotic corticosteroids inhibit the pituitary gland, the pituitary gland does not secrete adrenal hormones direction. The adrenal glands do not work long days will shrink, no longer functional secretion of endogenous steroids. When you stop taking steroids exotic body lacks endogenous steroids suddenly be granted adrenal insufficiency, severe if not promptly treated can lead to death. So can not use oral corticosteroids to treat sustained VMDU.

Use of synthetic steroids fluticason, beclomethason, Budesonid by inhalation or nebulized (collectively inhaled corticosteroids), the drug will have in place a very strong effect, reduces inflammatory mediators, should reduce the itching, sneezing breath, runny nose, watery eyes, mucous membranes line, stuffy nose. A very small portion of the drug (10%) from the nose can go inside the body, but because of the rapid metabolism of steroids in the liver substance or no biological effects are very low systemic bioavailability lower body, no systemic toxicity such as drinking. Thus, the inhaled corticosteroids are the unique balance between treatment effect and safety.

Use of inhaled or nebulized (negative particles such as fog) on the nasal mucosa. Inhaled corticosteroids are usually effective immediately within 24-48 hours. But to have full effect to a period necessary (such as 2-4 days with fluticason, 3-7 days to bude sonid). Treatment should be constant over time gap between the appropriate use to be effective. Such as with fluticason used 2 times per day (8 am and 8 pm, and then be able to maintain a lower dose per day 1).

For drug effective early beginning, inhaled corticosteroids may coordinate with antihistamines, bronchodilators, coricoid drink; can then stop the drug combination, the only inhaled corticosteroids maintained.

Inhaled corticosteroids are not toxic but can cause some unwanted effects such as headache, sore throat, nasal irritation, sneezing, coughing, nausea, vomiting, nosebleeds, skin rash, itching, swelling face, anaphylaxis, but are less common.

Type inhaler if prolonged use of oral corticosteroids attached can also be poisoned body, the expression: strengthen the adrenal cortex, if you stop taking the drug can cause adrenal insufficiency. Be careful when combined with oral corticosteroids in the treatment of rhinitis or nasal inflammation associated with more asthma (as mentioned above).

For pregnant women, breast-feeding: Pregnant steroids harmful, damaging information on breastfeeding milk. However, inhaled corticosteroids should not see this phenomenon can still be used for pregnant women to breastfeed. No inhaled corticosteroid treatment VMDU for children under 12 years of age, own beclomethason not for children under 6 years of age. Inhaled corticosteroids virtually non-toxic, can be used long-term stable disease, is considered the mainstay of treatment VMDU.

Technically medication

Puffs of inhaled dose aerosol properties (such as inhaled corticosteroids). Do not take the first spray in the nose, but only the first set at the beginning of nasal spray to spray (droplets or mist) into the right nasal mucosa.

Aqueous solution drips, drops dose calculation (such as nasal fluids). Use two fingers grip slightly, according to the drug flow drops, rather than the hand or fingers to squeeze more powerful streaming medicine, do not count, will lead to an overdose. Need help your child, because a child under 12 years is difficult to comply with the above techniques are very simple though. Using improper technique will not guarantee the dose or overdose, it is difficult to be effective, easy to poisoning.

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